Several other analyses of the evidence have been done in the last few years (2012 or later), and like the 2018 analysis and the AHRQ report, most found little or no evidence for a protective effect of omega-3 supplements against heart disease.They did not find evidence that omega-3s can reduce the risk of heart attacks or death from heart disease. Government’s Agency for Healthcare Research and Quality (AHRQ) did a comprehensive evaluation of 98 studies of omega-3s and heart disease, including both diet and supplementation studies. A 2018 analysis of 10 major omega-3 supplementation studies (77,917 total participants, all at high risk of heart disease), each of which involved at least 500 participants and a treatment duration of at least a year, found no evidence that omega-3s could reduce the risk of fatal or nonfatal coronary heart disease.A 2011 evaluation of 17 studies indicated that people who eat seafood (fish and shellfish) one to four times a week are less likely to die of heart disease than those who rarely or never eat seafood.If you’re taking medicine that affects blood clotting or if you’re allergic to fish or shellfish, consult your health care provider before taking omega-3 supplements.There’s conflicting evidence on whether omega-3s might influence the risk of prostate cancer.Omega-3s usually produce only mild side effects, if any.What do we know about the safety of omega-3 supplements?
For most other conditions for which omega-3 supplements have been studied, the evidence is inconclusive or doesn’t indicate that omega-3s are beneficial.Omega-3 supplements have not been convincingly shown to slow the progression of the eye disease age-related macular degeneration.Omega-3 supplements may help relieve symptoms of rheumatoid arthritis.High doses of omega-3s can reduce levels of triglycerides.However, people who eat seafood one to four times a week are less likely to die of heart disease. Research indicates that omega-3 supplements don’t reduce the risk of heart disease.What do we know about the effectiveness of omega-3 supplements? How much do we know about omega-3 fatty acids (omega-3s)?Įxtensive research has been done on omega-3s, especially the types found in seafood (fish and shellfish) and fish oil supplements.
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